Here are the differences between PCSX2 for Konami Python 2 and (a purposed) PCSX2 for Konami Python 1.
PCSX2 for Konami Python 2 supports py2 files (configuration includes raw HDD's, dongles, etc.)
PCSX2 for Konami Python 1 supports a combination of ROMs and CHDs.
Oh, here's what I forgot over a year ago: It turns out that Mocap Golf actually runs on Konami Viper, not Konami Python.